Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair

INTRODUCTION: Transposition of the great arteries (TGA) is a cyanotic congenital heart defect that requires surgical correction, with the use of cardiopulmonary-bypass (CPB), usually within 3 weeks of life. The use of CPB in open heart surgery results in brain hypoperfusion and in a powerful systemi...

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Publicado en:Metabolomics
Autores principales: Simonato, Manuela, Fochi, Igor, Vedovelli, Luca, Giambelluca, Sonia, Carollo, Cristiana, Padalino, Massimo, Carnielli, Virgilio P., Cogo, Paola
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817811/
https://ncbi.nlm.nih.gov/pubmed/31659512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-019-1605-3
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