Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds

PURPOSE: To investigate the role of Gremlin-1, which is an endogenous antagonist of the bone morphogenetic protein (BMP) signaling pathway, in inducing epithelium-mesenchymal transition (EMT) in fetal RPE cells after repeated wounds. METHODS: Subconfluent repetitive passages in fetal RPE cells were...

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Veröffentlicht in:Mol Vis
Hauptverfasser: Li, Duo, Yuan, Dongqing, Shen, Han, Mao, Xiying, Yuan, Songtao, Liu, Qinghuai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817737/
https://ncbi.nlm.nih.gov/pubmed/31700227
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