Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

BACKGROUND: Inflammatory processes contribute to the pathophysiology of multiple chronic conditions. Genetic factors play a crucial role in modulating the inflammatory load, but the exact mechanisms are incompletely understood. OBJECTIVE: To assess genetic determinants of 16 circulating cytokines an...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Sliz, Eeva, Kalaoja, Marita, Ahola-Olli, Ari, Raitakari, Olli, Perola, Markus, Salomaa, Veikko, Lehtimäki, Terho, Karhu, Toni, Viinamäki, Heimo, Salmi, Marko, Santalahti, Kristiina, Jalkanen, Sirpa, Jokelainen, Jari, Keinänen-Kiukaanniemi, Sirkka, Männikkö, Minna, Herzig, Karl-Heinz, Järvelin, Marjo-Riitta, Sebert, Sylvain, Kettunen, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Complex Traits
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817708/
https://ncbi.nlm.nih.gov/pubmed/31217265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2018-105965
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