Minocycline Ameliorates Depressive-Like Behavior and Demyelination Induced by Transient Global Cerebral Ischemia by Inhibiting Microglial Activation

Global cerebral ischemia (GCI) commonly occurs in the elderly. Subcortical white matter lesions and oligodendrocyte (OLG) loss caused by cerebral ischemia have been implicated in the development of post-ischemic depression and cognitive impairment. OLGs are necessary for axonal myelination; the disr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Du, Bingying, Li, Hailong, Zheng, Huiwen, Fan, Cunxiu, Liang, Meng, Lian, Yongjie, Wei, Zelan, Zhang, Yanbo, Bi, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817504/
https://ncbi.nlm.nih.gov/pubmed/31695615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01247
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