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Association between SMAD3 gene rs12901499 polymorphism and knee osteoarthritis in a Chinese population

BACKGROUND: Many studies have revealed that transforming growth factor‐beta (TGF‐β) signals play important roles in maintaining normal status of articular cartilage in human osteoarthritis (OA). However, SMAD3 had inhibitory effect on TGF‐β‐induced chondrocyte maturation. METHOD: To evaluate the ass...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Zhang, Li, Zhang, Limin, Zhang, Haiqin, Wang, Wenjun, Zhao, You
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817063/
https://ncbi.nlm.nih.gov/pubmed/29315792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22383
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