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Mutagenic primer‐based PCR‐RFLP assay for genotyping IRGM gene promoter variant rs4958843 (C/T)

BACKGROUND: Single‐nucleotide polymorphisms play an important role in the susceptibility of many diseases, evolutionary studies, and genetic mapping. The rs4958843 in IRGM promoter is associated with tuberculosis and Crohn's disease. As this SNP is not present in any of the restriction sites, P...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Sharma, Ambika, Changotra, Harish
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816862/
https://ncbi.nlm.nih.gov/pubmed/29178192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22346
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