Carrier-Free CXCR4-Targeted Nanoplexes Designed for Polarizing Macrophages to Suppress Tumor Growth

INTRODUCTION: Treatment options for cancer metastases, the primary cause of cancer mortality, are limited. The chemokine receptor CXCR4 is an attractive therapeutic target in cancer because it mediates metastasis by inducing cancer cell and macrophage migration. Here we engineered carrier-free CXCR4...

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Udgivet i:Cell Mol Bioeng
Main Authors: Deci, Michael B., Liu, Maixian, Gonya, Jacqueline, Lee, Christine J., Li, Tingyi, Ferguson, Scott W., Bonacquisti, Emily E., Wang, Jinli, Nguyen, Juliane
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816770/
https://ncbi.nlm.nih.gov/pubmed/31719921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-019-00589-w
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