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A major interspecies difference in the ionic selectivity of megakaryocyte Ca(2+)-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01

TMEM16F is a surface membrane protein critical for platelet procoagulant activity, which exhibits both phospholipid scramblase and ion channel activities following sustained elevation of cytosolic Ca(2+). The extent to which the ionic permeability of TMEM16F is important for platelet scramblase resp...

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Detalhes bibliográficos
Publicado no:Platelets
Main Authors: Taylor, Kirk A., Mahaut-Smith, Martyn P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816474/
https://ncbi.nlm.nih.gov/pubmed/31008669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2019.1595560
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