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Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing

Chromatin Assembly Factor I (CAF-I) plays a central role in the reassembly of H3/H4 histones during DNA replication. In S. cerevisiae CAF-I is not essential and its loss is associated with reduced gene silencing at telomeres and increased sensitivity to DNA damage. Two kinases, Cyclin Dependent Kina...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Rowlands, Hollie, Shaban, Kholoud, Cheng, Ashley, Foster, Barret, Yankulov, Krassimir
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816422/
https://ncbi.nlm.nih.gov/pubmed/31564230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1673100
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