Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine

Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients, and most tumors exhibit inherent heterogeneity. Hence, imprecise targeting commonly results in side effects, reduced efficacy, and drug resis...

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Dades bibliogràfiques
Publicat a:Front Genet
Autors principals: Conforte, Alessandra J., Tuszynski, Jack Adam, da Silva, Fabricio Alves Barbosa, Carels, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816034/
https://ncbi.nlm.nih.gov/pubmed/31695721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00930
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