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Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine

Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients, and most tumors exhibit inherent heterogeneity. Hence, imprecise targeting commonly results in side effects, reduced efficacy, and drug resis...

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書目詳細資料
發表在:Front Genet
Main Authors: Conforte, Alessandra J., Tuszynski, Jack Adam, da Silva, Fabricio Alves Barbosa, Carels, Nicolas
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816034/
https://ncbi.nlm.nih.gov/pubmed/31695721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00930
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