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Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine
Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients, and most tumors exhibit inherent heterogeneity. Hence, imprecise targeting commonly results in side effects, reduced efficacy, and drug resis...
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| 發表在: | Front Genet |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816034/ https://ncbi.nlm.nih.gov/pubmed/31695721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00930 |
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