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Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine
Traditional approaches to cancer therapy seek common molecular targets in tumors from different patients. However, molecular profiles differ between patients, and most tumors exhibit inherent heterogeneity. Hence, imprecise targeting commonly results in side effects, reduced efficacy, and drug resis...
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| Pubblicato in: | Front Genet |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816034/ https://ncbi.nlm.nih.gov/pubmed/31695721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00930 |
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