Genome landscapes of rectal cancer before and after preoperative chemoradiotherapy

Resistance to preoperative chemoradiotherapy (CRT) is a major obstacle to cancer treatment in patients with locally advanced rectal cancer. This study was to explore genome alterations in rectal cancer under CRT stress. Methods: Whole-exome sequencing (WES) was performed on 28 paired tumors collecte...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Yang, Jie, Lin, Yuan, Huang, Ying, Jin, Jing, Zou, Shuangmei, Zhang, Xiaolong, Li, Hongmin, Feng, Ting, Chen, Jinna, Zuo, Zhixiang, Zheng, Jian, Li, Yexiong, Gao, Ge, Wu, Chen, Tan, Wen, Lin, Dongxin
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815957/
https://ncbi.nlm.nih.gov/pubmed/31660073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37794
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