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Preclinical evaluation of exemestane as a novel chemotherapy for gastric cancer
CYP19A1/aromatase (Ar) is a prognostic biomarker of gastric cancer (GCa). Ar is a critical enzyme for converting androstenedione to oestradiol in the steroidogenesis cascade. For decades, Ar has been targeted with Ar inhibitors (ARIs) in gynaecologic malignancies; however, it is unexplored in GCa. A...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815818/ https://ncbi.nlm.nih.gov/pubmed/31557413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14605 |
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