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DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild‐type NSCLC cells to AZD9291

DYRK1A is considered a potential cancer therapeutic target, but the role of DYRK1A in NSCLC oncogenesis and treatment requires further investigation. In our study, high DYRK1A expression was observed in tumour samples from patients with lung cancer compared with normal lung tissues, and the high lev...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Mol Med
Egile Nagusiak: Li, Yang‐ling, Ding, Ke, Hu, Xiu, Wu, Lin‐wen, Zhou, Dong‐mei, Rao, Ming‐jun, Lin, Neng‐ming, Zhang, Chong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815810/
https://ncbi.nlm.nih.gov/pubmed/31454149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14609
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