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Structure of the DASH/Dam1 Complex Shows its Role at the Yeast Kinetochore-Microtubule Interface

Kinetochores connect mitotic-spindle microtubules with chromosomes, allowing microtubule depolymerization to pull chromosomes apart during anaphase while resisting detachment as the microtubule shortens. The DASH/Dam1 heterodecamer (DASH/Dam1c), an essential component of yeast kinetochores, assemble...

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Publicat a:Science
Autors principals: Jenni, Simon, Harrison, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815591/
https://ncbi.nlm.nih.gov/pubmed/29724956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar6436
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