Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo

For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlying this neuronal migration is still poorly understood. The dynein-adaptor protein BICD2 is a...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Will, Lena, Portegies, Sybren, van Schelt, Jasper, van Luyk, Merel, Jaarsma, Dick, Hoogenraad, Casper C.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815425/
https://ncbi.nlm.nih.gov/pubmed/31655624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0827-y
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