Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90(rsk)-CREB pathway

BACKGROUND: Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is one of the new therapeutic strategies for treating ischemic brain and heart tissues. However, the poor survival rate of transplanted BMSCs in ischemic tissue, due to high levels of reactive oxygen species (ROS), limits t...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Fang, Jiankang, Zhao, Xia, Li, Shuai, Xing, Xingan, Wang, Haitao, Lazarovici, Philip, Zheng, Wenhua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815409/
https://ncbi.nlm.nih.gov/pubmed/31655619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1419-2
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