Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation

Lipopolysaccharide (LPS)–induced encephalopathy induces neuroinflammation. Long-term neuroinflammation is associated with aging and subsequent cognitive impairment (CI). We treated rats that had LPS-induced neuroinflammation with OKN-007, with an anti-inflammatory agent currently considered an anti-...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Towner, Rheal A., Saunders, Debra, Smith, Nataliya, Gulej, Rafal, McKenzie, Tyler, Lawrence, Brandy, Morton, Kathryn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815317/
https://ncbi.nlm.nih.gov/pubmed/31478121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00094-y
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