Functional Profiling of Nucleotide Excision Repair in Breast Cancer

Homologous recombination deficiency conferred by alterations in BRCA1 or BRCA2 are common in breast tumors and can drive sensitivity to platinum chemotherapy and PARP inhibitors. Alterations in nucleotide excision repair (NER) activity can also impact sensitivity to DNA damaging agents, but NER acti...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Rajkumar-Calkins, Anne S., Szalat, Raphael, Dreze, Matija, Khan, Iman, Frazier, Zoë, Reznichenkov, Elizaveta, Schnorenberg, Mathew R., Tsai, Yi-Fang, Nguyen, Huy, Kochupurakkal, Bose, D’Andrea, Alan, Shapiro, Geoff I, Lazaro, Jean-Bernard, Mouw, Kent W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815104/
https://ncbi.nlm.nih.gov/pubmed/31499327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102697
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