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Brain pyrimidine nucleotide synthesis and Alzheimer disease
Many patients suffering late-onset Alzheimer disease show a deficit in respiratory complex IV activity. The de novo pyrimidine biosynthesis pathway connects with the mitochondrial respiratory chain upstream from respiratory complex IV. We hypothesized that these patients would have decreased pyrimid...
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| 出版年: | Aging (Albany NY) |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814620/ https://ncbi.nlm.nih.gov/pubmed/31560653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102328 |
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