TRIM59 loss in M2 macrophages promotes melanoma migration and invasion by upregulating MMP-9 and Madcam1

The culture supernatant from macrophages overexpressing TRIM59 has a cytotoxic effect on melanoma, but the mechanism remains unclear. To investigate whether deletion of TRIM59 in macrophages affects the metastatic potential of melanoma cells, we polarized control and TRIM59-deficient bone marrow-der...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Tian, Yuan, Guo, Yantong, Zhu, Pei, Zhang, Dongxu, Liu, Shanshan, Tang, Mengyan, Wang, Yuanxin, Jin, Zheng, Li, Dong, Yan, Dongmei, Li, Guiying, Zhu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814609/
https://ncbi.nlm.nih.gov/pubmed/31600735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102351
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