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Female Platelets Have Distinct Functional Activity Compared to Male Platelets: Implications in Transfusion Practice and Treatment of Trauma-Induced Coagulopathy

BACKGROUND: Females are hypercoagulable and have survival benefit in trauma-induced coagulopathy (TIC). The mechanism for this sex-specific hypercoagulability is unknown. Platelets and platelet function are central in providing hemostatic potential and are the largest contributor to clot strength. L...

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Bibliografiske detaljer
Udgivet i:J Trauma Acute Care Surg
Main Authors: Coleman, Julia R, Moore, Ernest E, Kelher, Marguerite R, Samuels, Jason M, Cohen, Mitchell J, Sauaia, Angela, Banerjee, Anirban, Silliman, Christopher C, Peltz, Erik
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814522/
https://ncbi.nlm.nih.gov/pubmed/31162329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002398
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