The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

Two types of monocytes, Ly6C(hi) and Ly6C(lo), infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6C(hi) and Ly6C(lo) cells, allowing these macrophages to perform dive...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hou, Xuezhou, Chen, Guobao, Bracamonte-Baran, William, Choi, Hee Sun, Diny, Nicola L., Sung, Jungeun, Hughes, David, Won, Taejoon, Wood, Megan Kay, Talor, Monica V., Hackam, David Joel, Klingel, Karin, Davogustto, Giovanni, Taegtmeyer, Heinrich, Coppens, Isabelle, Barin, Jobert G., Čiháková, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813836/
https://ncbi.nlm.nih.gov/pubmed/31269438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.007
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