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The role of exosomal PD-L1 in tumor progression and immunotherapy
Programmed death ligand 1 (PD-L1), a type I transmembrane protein, binds to its receptor PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis. In contrast, tumor cells highly express PD-L1, which binds to receptor PD-1 expressed on activated T cells, leading to i...
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| Publicado no: | Mol Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813045/ https://ncbi.nlm.nih.gov/pubmed/31647023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1074-3 |
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