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Ultrasensitive Detection of Clostridioides difficile Toxins in Stool by Use of Single-Molecule Counting Technology: Comparison with Detection of Free Toxin by Cell Culture Cytotoxicity Neutralization Assay

Laboratory tests for Clostridioides difficile infection (CDI) rely on the detection of free toxin or molecular detection of toxin genes. The Singulex Clarity C. diff toxins A/B assay is a rapid, automated, and ultrasensitive assay that detects C. difficile toxins A and B in stool. We compared CDI as...

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Veröffentlicht in:J Clin Microbiol
Hauptverfasser: Hansen, Glen, Young, Stephen, Wu, Alan H. B., Herding, Emily, Nordberg, Vickie, Mills, Ray, Griego-Fullbright, Christen, Wagner, Aaron, Ong, Chui Mei, Lewis, Shawna, Yoon, Joseph, Estis, Joel, Sandlund, Johanna, Friedland, Emily, Carroll, Karen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812992/
https://ncbi.nlm.nih.gov/pubmed/31434724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00719-19
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