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Phylogenetic correlations can suffice to infer protein partners from sequences
Determining which proteins interact together is crucial to a systems-level understanding of the cell. Recently, algorithms based on Direct Coupling Analysis (DCA) pairwise maximum-entropy models have allowed to identify interaction partners among paralogous proteins from sequence data. This success...
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| Izdano u: | PLoS Comput Biol |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6812855/ https://ncbi.nlm.nih.gov/pubmed/31609984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007179 |
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