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The Rise of NK Cell Checkpoints as Promising Therapeutic Targets in Cancer Immunotherapy

Checkpoint immunotherapy that targets inhibitory receptors of T cells, thereby reversing the functional exhaustion of T cells, marks a breakthrough in anticancer therapy. The success of T cell-directed checkpoint inhibitors of CTLA-4 and PD-1/PD-L1 has opened a new approach for cancer immunotherapy...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sun, Haoyu, Sun, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812684/
https://ncbi.nlm.nih.gov/pubmed/31681269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02354
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