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Reconstitution, Characterization, and [2Fe-2S] Cluster Exchange Reactivity of a Holo Human BOLA3 Homodimer

A new class of mitochondrial disease has been identified and characterized as Multiple Mitochondrial Dysfunctions Syndrome (MMDS). Four different forms of the disease have each been attributed to point mutations in proteins involved in iron-sulfur (Fe-S) biosynthesis; in particular, MMDS2 has been a...

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Vydáno v:J Biol Inorg Chem
Hlavní autoři: Wachnowsky, Christine, Rao, Brian, Sen, Sambuddha, Fries, Brian, Howard, Cecil J., Ottesen, Jennifer J., Cowan, J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812618/
https://ncbi.nlm.nih.gov/pubmed/31486956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01713-x
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