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An efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research
We propose a new genome-wide association test for mixed binary and continuous phenotypes that uses an efficient numerical method to estimate the empirical distribution of the Fisher’s combination statistic under the null hypothesis. Our simulation study shows that the proposed method controls the ty...
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| Опубликовано в: : | Stat Methods Med Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6812509/ https://ncbi.nlm.nih.gov/pubmed/27215414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280216647422 |
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