Berberine (BBR) Attenuated Palmitic Acid (PA)-Induced Lipotoxicity in Human HK-2 Cells by Promoting Peroxisome Proliferator-Activated Receptor a (PPAR-a)

BACKGROUND: Berberine (BBR), a natural alkaloid isolated from Coptis chinensis, has frequently been reported as an antidiabetic reagent, partly due to its lipid-lowering activity. Evidence suggests that BBR ameliorates palmitate-induced lipid deposition and apoptosis in renal tubular epithelial cell...

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Detalles Bibliográficos
Publicado en:Med Sci Monit
Autores principales: Wu, Yueyue, Chen, Fangyuan, Huang, Xinmei, Zhang, Rui, Yu, Zhiyan, Chen, Zaoping, Liu, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812469/
https://ncbi.nlm.nih.gov/pubmed/31607744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.916686
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