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A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients

Rationale: Neutrophil extracellular traps (NETs) are important in the host defense against infection, but they also promote intravascular coagulation and multiorgan failure in animal models. Their clinical significance remains unclear, and available assays for patient care lack specificity and relia...

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Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Abrams, Simon T., Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Lane, Steven, Welters, Ingeborg D., Wang, Guozheng, Toh, Cheng-Hock
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812439/
https://ncbi.nlm.nih.gov/pubmed/31162936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201811-2111OC
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