A real-time ex vivo model (eIBUB) for optimizing intraperitoneal drug delivery as an alternative to living animal models

BACKGROUND: Optimization of intraperitoneal drug delivery systems requires functional models. We proposed the Inverted Bovine Urinary Bladder Model (IBUB), but IBUB does not allow repeated measurements over time and there is a significant biological variability between organs. METHODS: A further dev...

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Dettagli Bibliografici
Pubblicato in:Pleura Peritoneum
Autori principali: Sautkin, Iaroslav, Solass, Wiebke, Weinreich, Frank-Jürgen, Königsrainer, Alfred, Schenk, Martin, Thiel, Karolin, Reymond, Marc A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: De Gruyter 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812219/
https://ncbi.nlm.nih.gov/pubmed/31667331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/pp-2019-0017
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