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Synthesis of New Cu Complex Based on Natural 5Z,9Z-Eicosadienoic Acid: Effective Topoisomerase I Inhibitor and Cytotoxin against the Cisplatin-Resistant Cell Line
[Image: see text] The complex (bipy)(2)Cu(5,9-eicd) was prepared by the reaction of Cu(OAc)(2) with 5Z,9Z-eicosadienoic acid and 2,2′-bipyridine in methanol. The new copper complex showed high antitumor activity in vitro toward A2780cis, A2780, Hek293, K562, HL60, Jurkat, and U937 cell lines and eff...
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| 出版年: | ACS Omega |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2019
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6812112/ https://ncbi.nlm.nih.gov/pubmed/31656933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02756 |
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