Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells

OBJECTIVE: Enteroendocrine cells (EECs) of the large intestine, found scattered in the epithelial layer, are known to express different hormones, with at least partial co-expression of different hormones in the same cell. Here we aimed to categorize colonic EECs and to identify possible targets for...

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Vydáno v:Mol Metab
Hlavní autoři: Billing, Lawrence J., Larraufie, Pierre, Lewis, Jo, Leiter, Andrew, Li, Joyce, Lam, Brian, Yeo, Giles SH., Goldspink, Deborah A., Kay, Richard G., Gribble, Fiona M., Reimann, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812004/
https://ncbi.nlm.nih.gov/pubmed/31668387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.09.001
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