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Synthetic Approach to the ABCD Ring System of Anticancer Agent Fredericamycin A via Claisen Rearrangement and Ring-Closing Metathesis as Key Steps

[Image: see text] A new synthetic strategy to the ABCD ring system of the anticancer agent fredericamycin A (NSC-305263) was realized by the Diels–Alder reaction and olefin metathesis as key steps. The tactics developed here for the construction of the ABCD ring system also involve double Claisen re...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Kotha, Sambasivarao, Cheekatla, Subba Rao, Fatma, Ambareen
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2019
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811863/
https://ncbi.nlm.nih.gov/pubmed/31656883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01178
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