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Potent Dopamine D(2) Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia

Antipsychotics that are potent dopamine (DA) D(2) receptor antagonists have been linked to elevated levels of nicotine dependence in smokers with schizophrenia. Because activation of D(2) receptors mediates motivation for nicotine, we examined whether potent D(2) antagonists would diminish nicotine’...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Whitton, Alexis E, Green, Alan I, Pizzagalli, Diego A, Roth, Robert M, Williams, Jill M, Brunette, Mary F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811816/
https://ncbi.nlm.nih.gov/pubmed/30690638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby185
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