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The novel cannabinoid CB(1) receptor agonist AM11101 increases food intake in female rats

BACKGROUND AND PURPOSE: Δ(9)‐tetrahydrocannabinol (THC) acts via cannabinoid CB(1) receptors to increase feeding. Here, we assessed the orexigenic effect of AM11101, a novel CB(1) receptor agonist designed to have a more favourable pharmacodynamic profile than THC. EXPERIMENTAL APPROACH: The acute,...

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Udgivet i:Br J Pharmacol
Main Authors: Ogden, Sean B., Malamas, Michael S., Makriyannis, Alexandros, Eckel, Lisa A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811743/
https://ncbi.nlm.nih.gov/pubmed/31328790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14797
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