Utility of Targeted, Amplicon-Based Deep Sequencing To Detect Resistance to First-Line Tuberculosis Drugs in Botswana

Multidrug-resistant tuberculosis (TB) is an alarming threat, and targeted deep sequencing (DS) may be an effective method for rapid identification of drug-resistant profiles, including detection of heteroresistance. We evaluated the sensitivity and specificity of targeted DS versus phenotypic drug s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wang, Qiao, Modongo, Chawangwa, Allender, Christopher, Engelthaler, David M., Warren, Robin M., Zetola, Nicola M., Shin, Sanghyuk S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Analytical Procedures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811446/
https://ncbi.nlm.nih.gov/pubmed/31405858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00982-19
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