Daily Dosing for Bedaquiline in Patients with Tuberculosis

The bedaquiline regimen for the treatment of multidrug-resistant tuberculosis (MDR-TB) in adults is a loading dose of 400 mg QD for 2 weeks followed by 200 mg thrice weekly (TIW) for 22 weeks. Most TB antibiotics administered with bedaquiline are given QD. Using pharmacokinetic simulations, we explo...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Salinger, David H., Nedelman, Jerry R., Mendel, Carl, Spigelman, Melvin, Hermann, David J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Clinical Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811417/
https://ncbi.nlm.nih.gov/pubmed/31451504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00463-19
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