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CreC Sensor Kinase Activation Enhances Growth of Escherichia coli in the Presence of Cephalosporins and Carbapenems

Mutants with enhanced growth in the presence of an antibiotic are more difficult to identify than mutants where the antibiotic’s MIC increases, because they are not amenable to lethal selection in vitro. We report that activatory mutations in the CreC signal sensor enhance growth of Escherichia coli...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Takebayashi, Yuiko, Taylor, Emma S., Whitwam, Sam, Avison, Matthew B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811401/
https://ncbi.nlm.nih.gov/pubmed/31451505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-19
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