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CreC Sensor Kinase Activation Enhances Growth of Escherichia coli in the Presence of Cephalosporins and Carbapenems

Mutants with enhanced growth in the presence of an antibiotic are more difficult to identify than mutants where the antibiotic’s MIC increases, because they are not amenable to lethal selection in vitro. We report that activatory mutations in the CreC signal sensor enhance growth of Escherichia coli...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Takebayashi, Yuiko, Taylor, Emma S., Whitwam, Sam, Avison, Matthew B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811401/
https://ncbi.nlm.nih.gov/pubmed/31451505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-19
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