In Vitro Activity of Rifampin, Rifabutin, Rifapentine, and Rifaximin against Planktonic and Biofilm States of Staphylococci Isolated from Periprosthetic Joint Infection

The in vitro activities of rifampin, rifabutin, rifapentine, and rifaximin were tested against 200 periprosthetic joint infection (PJI)-associated staphylococci. Seven rifampin-resistant isolates had MICs of ≥4 μg/ml. Three isolates had rifampin MICs of 0.25 to 1 μg/ml and harbored an Asp471Gly RpoB...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Albano, Mariana, Karau, Melissa J., Greenwood-Quaintance, Kerryl E., Osmon, Douglas R., Oravec, Caitlin P., Berry, Daniel J., Abdel, Matthew P., Patel, Robin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811393/
https://ncbi.nlm.nih.gov/pubmed/31451499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00959-19
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