607. Scope and Predictive Genetic/Phenotypic Signatures of “Bicarbonate [NaHCO3]-Responsivity” and β-Lactam Sensitization among Methicillin-Resistant Staphylococcus aureus (MRSA)

BACKGROUND: Selected MRSA strains become susceptible to β-lactams (e.g., oxacillin [OX]; cefazolin [CFZ]) in vitro when tested in a standard medium (cation-adjusted Mueller–Hinton Broth; CA-MHB) supplemented with NaHCO(3) (“NaHCO(3)-responsivity”). In vivo activity of β-lactams was demonstrated for...

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Publicado no:Open Forum Infect Dis
Main Authors: Ceren. Ersoy, Selvi, Zapata-Davila, Brianne, Otmishi, Mariam, Milan, Vanessa, Li, Liang, Chambers, Henry, Xiong, Yan, Bayer, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811183/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.676
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