681. In vitro Activity of the β-Lactamase Inhibitor QPX7728 in Combination with Several β-Lactams Against Acinetobacter baumannii (AB) and Pseudomonas aeruginosa (PSA)

BACKGROUND: QPX7728 (QPX) is a novel broad-spectrum boron-containing inhibitor of serine- and metallo-β-lactamases (MBLs). We evaluated the in vitro activity of QPX combined with several β-lactams against carbapenem-resistant AB (CRAB) and PSA clinical isolates with varying β-lactam resistance mecha...

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Publicado en:Open Forum Infect Dis
Main Authors: Lomovskaya, Olga, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk J, Castanheira, Mariana
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811169/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.749
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