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Increased Akt signaling in the fat body of Anopheles stephensi extends lifespan and increases lifetime fecundity through modulation of insulin-like peptides

Insulin-like peptides (ILPs) and the insulin/insulin-like growth factor 1 signaling (IIS) cascade regulate numerous physiological functions, including lifespan, reproduction, immunity, and metabolism, in diverse eukaryotes. We previously demonstrated that in female Anopheles stephensi and Aedes aegy...

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Bibliographic Details
Published in:J Insect Physiol
Main Authors: Hun, Lewis, Luckhart, Shirley, Riehle, Michael A.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810901/
https://ncbi.nlm.nih.gov/pubmed/31445957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinsphys.2019.103932
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