A human IgE antibody binding site on Der p 2 for the design of a recombinant allergen for immunotherapy

Der p 2 is one of the most important allergens from the house dust mite Dermatophagoides pteronyssinus. Identification of human IgE antibody binding epitopes can be used for rational design of allergens with reduced IgE reactivity for therapy. Antigenic analysis of Der p 2 was performed by site-dire...

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Pubblicato in:J Immunol
Autori principali: Glesner, Jill, Kapingidza, A Brenda, Godzwon, Magdalena, Offermann, Lesa R, Mueller, Geoffrey A, DeRose, Eugene F, Wright, Paul, Richardson, Crystal M, Woodfolk, Judith A, Vailes, Lisa D, Wünschmann, Sabina, London, Robert E, Chapman, Martin D, Ohlin, Mats, Chruszcz, Maksymilian, Pomés, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810898/
https://ncbi.nlm.nih.gov/pubmed/31554696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900580
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