691. Activity of TNP-2092 Against Biofilms Formed by Prosthetic Joint Infection-Associated Staphylococci

BACKGROUND: Infection occurs in ~1–2% of prosthetic joint replacement surgeries, with staphylococci being the most common cause. TNP-2092 is an investigational drug composed of rifamycin and quinolizinone pharmacophores conjugated via a stable linker. Here, we determined TNP-2092’s in vitro activity...

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Publié dans:Open Forum Infect Dis
Auteurs principaux: Fisher, Cody, Schmidt-Malan, Suzannah, Yuan, Ying, He, Shijie, Ma, Zhenkun, Patel, Robin
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810892/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.759
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