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Rhinovirus -induced SIRT-1 via TLR2 regulates subsequent type I and type III interferon responses in airway epithelial cells

Interferon (IFN) responses to viral infection is necessary to establish intrinsic antiviral state, but, if unchecked can lead to heightened inflammation. Recently, we showed that TLR2 activation contributes to limitation of rhinovirus (RV)-induced IFN response in the airway epithelial cells. We also...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Xander, Nathaniel, Vari, Hymavathi Reddy, Eskandar, Rewees, Li, Wuyan, Bolla, Sudhir, Marchetti, Nathaniel, Sajjan, Umadevi S.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810856/
https://ncbi.nlm.nih.gov/pubmed/31548332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900165
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