2607. Establishment of a Novel High-Throughput Fungal Infection Model in Zebrafish Larvae by Controlled Ablation of Epithelial Cells

BACKGROUND: Efficient animal models are needed in order to investigate fungal pathogenicity and antifungal therapy in the context of epithelial injury, e.g., due to anticancer chemotherapy. Using a Gal4 enhancer trap (GET) zebrafish line facilitating metronidazole (MTZ)-inducible ablation of epithel...

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Библиографические подробности
Опубликовано в: :Open Forum Infect Dis
Главные авторы: Wurster, Sebastian, Ruiz, Oscar E, Tatara, Alexander M, Samms, Krystin M, Kim Nguyen, Anh, D. Albert, Nathaniel, H. Kahan, Philip, Mikos, Antonios G, Eisenhoffer, George T, Kontoyiannis, Dimitrios P
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810349/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.2285
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