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Effectiveness of Immune Checkpoint Inhibitors in Transplant Recipients with Progressive Multifocal Leukoencephalopathy

Antibodies against PD1 have been used to treat progressive multifocal leukoencephalopathy (PML), a rare brain disease caused by JC virus. We used these antibodies (nivolumab) to treat PML in 3 kidney transplant recipients. All died within 8 weeks of diagnosis. Hence, nivolumab did not improve PML ou...

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Detalles Bibliográficos
Publicado en:Emerg Infect Dis
Main Authors: Medrano, Chloé, Vergez, François, Mengelle, Catherine, Faguer, Stanislas, Kamar, Nassim, Del Bello, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado: Centers for Disease Control and Prevention 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810212/
https://ncbi.nlm.nih.gov/pubmed/31625858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2511.190705
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