400. Comparison of Tolerance and Microbiological Efficacy of Cefepime and Piperacillin/Tazobactam in Combination with Vancomycin as Empirical Antimicrobial Therapy of Prosthetic Joint Infection: A Propensity-Matched Cohort Study

BACKGROUND: The use of piperacillin/tazobactam with vancomycin as empirical antimicrobial therapy (EAT) for prosthetic joint infection (PJI) has been associated with an increased risk of acute kidney injury (AKI), leading to propose cefepime as an alternative since 2017 in our reference center. The...

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Publicat a:Open Forum Infect Dis
Autors principals: Triffault-Fillit, Claire, Mabrut, Eugenie, Corbin, Karine, Becker, Agathe, Braun, Evelyne, Tod, Michel, Goutelle, Sylvain, Henri Fessy, Michel, Dupieux, Celine, Laurent, Frederic, Lustig, Sebastien, Chidiac, Christian, Ferry, Tristan, Valour, Florent
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809934/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.473
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