124. Impact of Levofloxacin MIC on Outcomes with Levofloxacin Step-down Therapy in Enterobacteriaceae Bloodstream Infections

BACKGROUND: The Clinical and Laboratory Standards Institute reduced the levofloxacin minimum inhibitory concentration (MIC) breakpoint from ≤2 to ≤0.5 mg/L for Enterobacteriaceae in 2019 guidelines. The reduction is based on Monte Carlo simulations for a levofloxacin dose of 750 mg daily. The aim of...

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Publicat a:Open Forum Infect Dis
Autors principals: White, Melissa, Lenzi, Kerry, Dutcher, Lauren S, Saw, Stephen, Morgan, Steven C, Binkley, Shawn, Athans, Vasilios, Cimino, Christo L, Degnan, Kathleen, Hamilton, Keith W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809892/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.199
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